abstract：:Procedures used in assessing patients with dementia in rural settings are little studied. Among all patients aged 65 years and older in the four primary care practices in Lake County, Oregon, dementia cases were identified from computerized office databases using preselected International Classification of Diseases, N...

journal_title：Journal of geriatric psychiatry and neurology

authors： Camicioli R,Willert P,Lear J,Grossmann S,Kaye J,Butterfield P

更新日期：2000-07-01 00:00:00

abstract：:To test the hypothesis that elderly patients who have surgery for femoral neck fractures may have delirium not only after surgery but before surgery, we prospectively investigated the perioperative temporal profile of cognitive function in such patients. We performed the Abbreviated Mental Test (AMT) six times in each...

journal_title：Journal of geriatric psychiatry and neurology

authors： Sato N,Sanuki M,Matsumoto C,Inoue K,Yuge O

更新日期：2000-01-01 00:00:00

abstract：:Late-life depression (LLD) is characterized by abnormalities in cerebral blood flow (CBF) and cerebral metabolic rate (CMR) for glucose. Unlike younger adults with major depression, global cortical CBF and CMR reductions have been reported in LLD. Patients with LLD are also characterized by topographic abnormalities, ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Nobler MS,Pelton GH,Sackeim HA

更新日期：1999-10-01 00:00:00

abstract：:To evaluate the importance of serum anticholinergic activity (SAA) in elderly patients who developed delirium following hospital admission, we performed a cross-sectional study with consecutively referred inpatients in a university geriatric medical ward. Sixty-one patients aged 66 to 95 years (mean age: 79.2+/-11.6; ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Mussi C,Ferrari R,Ascari S,Salvioli G

更新日期：1999-07-01 00:00:00

abstract：:Psychogeriatric patients are mentally affected by a heterogeneous group of diseases, traditionally classified as functional or organic brain disorders (OBDs). Here, we evaluate screening procedures with respect to revelation of underlying OBD. Fifty consecutive patients admitted to a psychogeriatric unit dedicated to ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Fladby T,Schuster M,Grønli O,Sjøholm H,Løseth S,Sexton H

更新日期：1999-04-01 00:00:00

abstract：:We studied 555 Alzheimer's disease patients on the Behavior Rating Scale for Dementia (BRSD), which uses informant interviews to measure behavioral pathology in demented patients. For the 45 items, ratings of present ranged from 5% to 66% of the subjects, with 39 rated present in at least 10%. Twenty-nine items were s...

journal_title：Journal of geriatric psychiatry and neurology

authors： Mack JL,Patterson MB,Tariot PN

更新日期：1999-01-01 00:00:00

abstract：:Delirium, or acute confusional state, represents a common, serious, potentially preventable and increasing problem for older hospitalized patients. This study is intended to improve overall understanding of the problem of delirium and thus to lessen its adverse impact on the older population. The specific aims of this...

journal_title：Journal of geriatric psychiatry and neurology

authors： Inouye SK

更新日期：1998-10-01 00:00:00

abstract：:The cause of Parkinson's disease (PD) is unknown. The major risk factors identified to date are family history, age, and elements of rural living. Nearly one-third of all PD cases are familial, a small subset of which appears autosomal dominant; however, the majority exhibit no clear inheritance pattern. Autosomal dom...

journal_title：Journal of geriatric psychiatry and neurology

authors： Payami H,Zareparsi S

更新日期：1998-07-01 00:00:00

abstract：:Although there is a broad base of literature on depression among elderly patients and on mania in younger patients, there is a relative paucity of information on bipolar disorder in the elderly population. While the quantities of data reflect the relative prevalences of these illnesses, there is evidence to suggest th...

journal_title：Journal of geriatric psychiatry and neurology

authors： Chen ST,Altshuler LL,Spar JE

更新日期：1998-04-01 00:00:00

abstract：:Behavioral disturbances are common in patients with dementia. Medical intervention is needed if, for example, these behaviors threaten a patient's safety or jeopardize his or her ability to perform activities of daily living. Typical antipsychotic agents are associated with troublesome adverse effects in the elderly (...

journal_title：Journal of geriatric psychiatry and neurology

authors： Pollock BG,Mulsant BH

更新日期：1998-01-01 00:00:00

abstract：:This study examined the degree to which demographic variables, psychiatric diagnosis, depression rating, and neuropsychological test performance predict adaptive kitchen behavior in geriatric psychiatry patients and normal elderly volunteers. Amixed group of 27 participants including 8 normal volunteers and 19 geriatr...

journal_title：Journal of geriatric psychiatry and neurology

authors： Benedict RH,Goldstein MZ,Dobraski M,Tannenhaus J

更新日期：1997-10-01 00:00:00

abstract：:As a result of the neuropathologic process of Alzheimer's disease (AD), significant changes occur in neuromotor function (e.g., paratonia and compulsive grasping). These changes become manifest in the moderately severe stage of AD, when patients begin to require ongoing assistance with activities of daily life (ADL), ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Souren LE,Franssen EH,Reisberg B

更新日期：1997-07-01 00:00:00

abstract：:The purpose of this preliminary report was to explore overall level and diurnal patterning of caregiver reports of abnormal behavior and to explore relationships with actigraphic measures of sleep/wake activity in Alzheimer's disease (AD) patients. Our primary behavioral measure was the Time-based Behavioral Disturban...

journal_title：Journal of geriatric psychiatry and neurology

authors： Friedman L,Kraemer HC,Zarcone V,Sage S,Wicks D,Bliwise DL,Sheikh J,Tinklenberg J,Yesavage JA

更新日期：1997-04-01 00:00:00

abstract：:It is important that clinicians who rate global change as part of Alzheimer's disease (AD) clinical drug trials agree on a relevant set of behaviors and information to be considered in formulating their rating. Yet, consensus among raters has been difficult to establish, and inter-rater reliability of clinical global ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Olin JT,Schneider LS,Doody RS,Clark CM,Ferris SH,Morris JC,Reisberg B,Schmitt FA

更新日期：1996-10-01 00:00:00

abstract：:We report the case of a 67-year-old woman who experienced a sudden onset of psychotic illness (i.e., prominent delusions and hallucinations) that has endured for approximately 3 years. As part of her neurobehavioral work-up, a SPECT scan revealed right frontal and left anterior temporal-lobe hypoperfusion. Serial neur...

journal_title：Journal of geriatric psychiatry and neurology

authors： Cloud BS,Carew TG,Rothenberg H,Malloy P,Libon DJ

更新日期：1996-07-01 00:00:00

abstract：:This study was conducted to determine whether or not diagnosis and treatment of delirium among patients treated with the intra-aortic balloon pump (IABP) correlates with the recording of this complication on discharge records. Since prior episodes of delirium are one of the few clear risk factors for future episodes o...

journal_title：Journal of geriatric psychiatry and neurology

authors： Glick RE,Sanders KM,Stern TA

更新日期：1996-04-01 00:00:00

abstract：:Late-onset Huntington's disease is more common than has been generally appreciated and is associated with a wide range of psychiatric symptoms and syndromes. Geriatric psychiatrists have an important role to play in establishing the diagnosis and providing guidance to elderly patients and their families as they strugg...

journal_title：Journal of geriatric psychiatry and neurology

authors： Shulman KI,Lennox A,Karlinsky H

更新日期：1996-01-01 00:00:00

abstract：:Neuroleptics remain the mainstay for the treatment of behavioral disturbance and psychotic symptoms in demented patients. The limited available data suggest that low-dose neuroleptics are significantly more efficacious than placebo, though the magnitude of the effect is moderate in most published studies. Demented pat...

journal_title：Journal of geriatric psychiatry and neurology

authors： Devanand DP,Levy SR

更新日期：1995-10-01 00:00:00

abstract：:Depressive disorders are a common problem in late life, requiring consistent and reliable screening by clinicians. Such screening should be based upon the most recent criteria available to facilitate diagnostic and nosologic agreement. This study presents a new screening instrument for geriatric depressive disorders b...

journal_title：Journal of geriatric psychiatry and neurology

authors： Kemp BJ,Adams BM

更新日期：1995-07-01 00:00:00

abstract：:Experimental pharmacotherapy of cognitive impairment in Alzheimer's disease has seen a recent proliferation of drug trials involving a wide variety of drugs. Many of the earlier studies focused on cholinergic agents. However, subsequent advances in basic and biological sciences have broadened the scope of therapeutic ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Patel SV

更新日期：1995-04-01 00:00:00

abstract：:This study was undertaken to evaluate the clinical response of geriatric patients with psychoses to the atypical neuroleptic drug, clozapine. Records of patients over 60 years of age (n = 12, all female) who had received clozapine over a 30-month period from selected hospitals in Western Pennsylvania were reviewed. Am...

journal_title：Journal of geriatric psychiatry and neurology

authors： Chengappa KN,Baker RW,Kreinbrook SB,Adair D

更新日期：1995-01-01 00:00:00

abstract：:Twenty-four geropsychiatric outpatients and 52 inpatients diagnosed with affective disorders (ADs) via psychiatric evaluation were administered the Structured Interview for Disorders of Personality-Revised (SIDP-R). A chart review yielded 1-year relapse rates for the inpatient sample. Data indicate a 63% personality d...

journal_title：Journal of geriatric psychiatry and neurology

authors： Molinari V,Marmion J

更新日期：1995-01-01 00:00:00

abstract：:To explore the extent to which treatment of depression affects survival, we evaluated the association between use of antidepressant medications and death rates among the residents of a large residential-care facility for the elderly using a retrospective record-review study (N = 624). One year survival, among those ta...

journal_title：Journal of geriatric psychiatry and neurology

authors： Katz IR,Parmelee PA,Beaston-Wimmer P,Smith BD

更新日期：1994-10-01 00:00:00

abstract：:In a randomized, placebo-controlled, double-blind study, 39 patients with depression with somatic symptoms were treated with hypericum extract LI 160. The therapy lasted for 4 weeks; the dosage was 300 mg three times daily. At the onset of the study as well as after 2 and 4 weeks, the following criteria were analyzed:...

journal_title：Journal of geriatric psychiatry and neurology

authors： Hübner WD,Lande S,Podzuweit H

更新日期：1994-10-01 00:00:00

abstract：:The influence of hypericin, hypericum total extract, and hypericum fractions on the activity of MAO and COMT, prepared in vitro from pork liver, were investigated in several concentration steps. An inhibition of MAO could be shown in the following concentrations (extract correlated to a mean molecular value of 500): h...

journal_title：Journal of geriatric psychiatry and neurology

authors： Thiede HM,Walper A

更新日期：1994-10-01 00:00:00

abstract：:The hypothesis that visual search tasks requiring effortful, serial processing are more sensitive to aging than those requiring relatively automatic, parallel processing was tested in 96 healthy adults who performed parallel and serial visual search tasks with fixed presentation times. Reaction times and error rates i...

journal_title：Journal of geriatric psychiatry and neurology

authors： Oken BS,Kishiyama SS,Kaye JA

更新日期：1994-07-01 00:00:00

abstract：:The authors reviewed the use of clozapine in eight patients over age 65 years with treatment-resistant psychoses. Six patients improved. Two patients became more confused. The authors suggest that clozapine be considered in treating elderly psychotic patients, and that its use need not be restricted to schizophrenic p...

journal_title：Journal of geriatric psychiatry and neurology

authors： Frankenburg FR,Kalunian D

更新日期：1994-04-01 00:00:00

abstract：:A new performance-based assessment instrument for evaluating function in patients with Alzheimer's disease (AD), the Cognitive Performance Test (CPT), is described. This instrument, based on Allen Cognitive Disability Theory, uses six common activities of daily living (ADL) tasks, for which the information-processing ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Burns T,Mortimer JA,Merchak P

更新日期：1994-01-01 00:00:00

abstract：:The shape and thickness of the third ventricles were studied with magnetic resonance imaging in 46 patients under evaluation for memory impairment. We compared this population with 23 subjects imaged for other reasons. The study group consisted of patients with diagnoses of probable dementia of the Alzheimer's type (D...

journal_title：Journal of geriatric psychiatry and neurology

authors： Powell AL,Mezrich RS,Coyne AC,Loesberg A,Keller I

更新日期：1993-10-01 00:00:00

abstract：:Findings from an exploratory study of the relationships between routine clinical laboratory tests and the clinical status of elderly patients living in a nursing home or congregate housing facility demonstrate that low albumin and anemia are associated with decreased survival and with self-care deficits, cognitive imp...

journal_title：Journal of geriatric psychiatry and neurology

authors： Katz IR,Beaston-Wimmer P,Parmelee P,Friedman E,Lawton MP

更新日期：1993-07-01 00:00:00

abstract：:In order to determine whether weight loss is a core symptom or secondary manifestation of Alzheimer's disease, we analyzed weight change in 81 outpatients with Alzheimer's disease. During a mean 2.9 years of observation, the mean absolute weight loss was 1.9 +/- 0.8 kg, and the mean weight loss per year was 0.7 +/- 0....

journal_title：Journal of geriatric psychiatry and neurology

authors： Du W,DiLuca C,Growdon JH

更新日期：1993-01-01 00:00:00

abstract：:This report describes a 70-year-old man with obstructive sleep apnea who deteriorated rapidly when nasal continuous positive airway pressure was begun. The patient was found to have normal-pressure hydrocephalus, which was possibly exacerbated by the nasal continuous positive airway pressure. A review of the literatur...

journal_title：Journal of geriatric psychiatry and neurology

authors： McNamara ME,Millman RP,Epstein MH,Fogel BS

更新日期：1992-10-01 00:00:00

abstract：:To measure the prevalence of noisy behavior as a nursing problem, a survey of head nurses was done in a chronic care hospital to identify patients whose vocalizing was frequently disturbing to other patients, staff, or visitors. We found 17 patients among the total of 154. Subsequently, the medical records of 13 survi...

journal_title：Journal of geriatric psychiatry and neurology

authors： Friedman R,Gryfe CI,Tal DT,Freedman M

更新日期：1992-10-01 00:00:00

abstract：:In an Italian kindred (family N), early onset Alzheimer's disease has been transmitted in a Mendelian autosomal fashion since the early 18th century. The age at death of affected members of the family varies widely, and was taken as an index of the age of expression, a measure of phenotypic variability. Either a gamma...

journal_title：Journal of geriatric psychiatry and neurology

authors： Bruni AC,Montesi MP,Salmon D,Gei G,Perre J,el Hachimi KH,Foncin JF

更新日期：1992-07-01 00:00:00

abstract：:The prevalence of psychiatric disorders and behavioral disturbances in nursing homes is high, but the relationship between the two is unknown. We studied 454 new admissions who were diagnosed by research psychiatrists using DSM-III-R criteria and compared patients who nursing staff designated as cooperative or uncoope...

journal_title：Journal of geriatric psychiatry and neurology

authors： Rovner BW,Steele CD,German P,Clark R,Folstein MF

更新日期：1992-04-01 00:00:00

abstract：:Fourteen patients who had cognitive dysfunction were studied with quantitative electroencephalography (EEG), single-photon emission computed tomography (SPECT), and several tests of intellectual and memory function, including the Wechsler Adult Intelligence Scale (WAIS), the Auditory Verbal Learning Test, and the Shor...

journal_title：Journal of geriatric psychiatry and neurology

authors： Wszolek ZK,Herkes GK,Lagerlund TD,Kokmen E

更新日期：1992-01-01 00:00:00

abstract：:The population resident in the skilled nursing home of a Veterans Administration Hospital on the 27th of June 1988 was screened for the presence of depression. Only 74% of the patients (59 of 80) were able to complete most of the screening battery: the Folstein Mini-Mental State Examination, the 15-item Geriatric Depr...

journal_title：Journal of geriatric psychiatry and neurology

authors： Baker FM,Miller CL

更新日期：1991-10-01 00:00:00

abstract：:Late-life depression may have different clinical features, hospital utilization patterns, and natural history, depending on whether the illness begins in midlife or late life. This historical cohort study examined three patient groups, late-onset geriatric depressed patients, early-onset geriatric depressed patients, ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Colenda CC,Trinkle D,Hamer RM,Jones S

更新日期：1991-07-01 00:00:00

abstract：:Rapid withdrawal of short to intermediate half-life benzodiazepines may be hazardous, particularly in the elderly. The use of carbamazepine to facilitate withdrawal has been reported in younger patients. We describe four elderly patients (average age, 72.5 years) who had each experienced at least one unsuccessful atte...

journal_title：Journal of geriatric psychiatry and neurology

authors： Swantek SS,Grossberg GT,Neppe VM,Doubek WG,Martin T,Bender JE

更新日期：1991-04-01 00:00:00

abstract：:Receiver operating characteristic analysis is a useful tool in validating a diagnostic marker. This technique was applied to a discriminant function model using selected electroencephalographic sleep measures (sleep maintenance, percentage of rapid-eye-movement sleep, and percentage of indeterminate non-rapid-eye-move...

journal_title：Journal of geriatric psychiatry and neurology

authors： Houck PR,Reynolds CF 3rd,Mazumdar S,Kupfer DJ

更新日期：1991-01-01 00:00:00